Cyclobutanecarboxylic acid, 1-[4-(trifluoromethyl)phenyl]- - Names and Identifiers
Cyclobutanecarboxylic acid, 1-[4-(trifluoromethyl)phenyl]- - Physico-chemical Properties
Molecular Formula | C12H11F3O2
|
Molar Mass | 244.21 |
Storage Condition | 2-8℃ |
Sensitive | IRRITANT |
MDL | MFCD10703525 |
Cyclobutanecarboxylic acid, 1-[4-(trifluoromethyl)phenyl]- - Introduction
1-[4-(Trifluoromethyl)phenyl]-cyclobutanecarboxylic acid is an organic compound commonly referred to as TFMA. Its chemical formula is C13H11F3O2 and its molecular weight is 260.22g/mol.
properties of TFMA: TFMA is a crystalline solid, white or light yellow crystalline powder. It has a melting point of 80-83°C, is soluble in ethanol, ether and dichloromethane, and is almost insoluble in water.
The use of TFMA: TFMA is often used as a chiral inducer and chiral catalyst in organic synthesis, and can be used to synthesize biologically active chiral compounds. It can also be used as pharmaceutical intermediates and pesticide intermediates.
Preparation of TFMA: The preparation of TFMA can be obtained by a multi-step reaction. A common synthesis method is to obtain the target product TFMA from p-trifluoromethylbenzoic acid through a ring-closing reaction.
TFMA safety information: TFMA is an organic compound, and you need to pay attention to operational safety when using it. It may be irritating to the skin, eyes and respiratory tract and should be protected from contact with appropriate protective equipment. Safe operating procedures must be followed during use or handling, and good ventilation conditions must be ensured.
Last Update:2024-04-10 22:29:15